Unexploited opportunities for phage therapy
نویسندگان
چکیده
منابع مشابه
Unexploited opportunities for phage therapy
(2015) Unexploited opportunities for phage therapy. A Surprising Twist on Bacteriophage Therapy Bacterial infections have always been a threat to human health. The first available systemic antibiotics, in early twentieth century, were initially seen as truly miraculous drugs, providing a powerful tool to combat bacterial infections and increasing human life span. Deluded by their exceptional an...
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متن کاملPhage therapy
Bacteriophage therapy, the use of viruses that infect bacteria as antimicrobials, has been championed as a promising alternative to conventional antibiotics. Although in the laboratory bacterial resistance against phages arises rapidly, resistance so far has been an only minor problem for the effectiveness of phage therapy. Resistance to antibiotics, however, has become a major issue after deca...
متن کاملSynergy as a rationale for phage therapy using phage cocktails
Where phages are used to treat bacterial contaminations and infections, multiple phages are typically applied at once as a cocktail. When two or more phages in the cocktail attack the same bacterium, the combination may produce better killing than any single phage (synergy) or the combination may be worse than the best single phage (interference). Synergy is of obvious utility, especially if it...
متن کاملRegulating phage therapy
I n a note published in The Lancet in December 1915, Frederic Twort described the discovery of an infectious, filterable agent that causes the glassy transformation and eventual killing of bacteria, now identified as Staphylococcus hyicus [1]. Two years later, Félix d’Herelle independently described an invisible microbe antagonistic to dysentery bacilli in a note to the Comptes Rendus de l’Acad...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2015
ISSN: 1663-9812
DOI: 10.3389/fphar.2015.00180